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List of substances for condition Group: Kidney

All Human Animal Risk/Association ReviewRows: 490

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Curcumin 📋✍⛔38299401Curcumin Inhibits Vasculogenic Mimicry Via Regulating ETS-1 in Renal Cell Carcinoma
Melatonin 📋✍⛔38713551Melatonin attenuates renal ischemia-reperfusion injury by regulating mitochondrial dynamics and autophagy through AMPK/DRP1
Resveratrol 📋✍⛔38529522A short treatment with resveratrol after a renal ischaemia-reperfusion injury prevents maladaptive repair and long-term chronic kidney disease in rats
Vitamin D3 📋✍⛔38558206Vitamin D inhibits ferroptosis and mitigates the kidney injury of prediabetic mice by activating the Klotho/p53 signaling pathway
Astragalosides 📋✍⛔38572426Astragaloside IV attenuates renal tubule injury in DKD rats via suppression of CD36-mediated NLRP3 inflammasome activation
Quercetin 📋✍⛔38726926The nephroprotective effect of Quercetin in Cyclophosphamide-induced renal toxicity might be associated with MAPK/ERK and NF-κB signal modulation activity
Berberine 📋✍⛔38705399Berberine alleviated contrast-induced acute kidney injury by mitophagy-mediated NLRP3 inflammasome inactivation in a mice model
Astragalus Root 📋✍⛔38404557The effect of Astragali Radix-Radix Angelica Sinensis on acute kidney injury: a network pharmacology and molecular docking study
Ginsenosides 📋✍⛔38683298Integrative informatics analysis identifies that ginsenoside Re improves renal fibrosis through regulation of autophagy
Vitamin C 📋✍⛔38518722Exploring the impact of high-altitude de-acclimatization on renal function: The roles of oxidative and endoplasmic reticulum stress in rat models
N-Acetyl Cysteine 📋✍⛔38004033N-Acetylcysteine Alleviates the Progression of Chronic Kidney Disease: A Three-Year Cohort Study
Nigella Sativa 📋✍⛔37009001Comparison of the anti-diabetic and nephroprotective activities of vitamin E, metformin, and Nigella sativa oil on kidney in experimental diabetic rats
Ginseng 📋✍⛔38460576Red ginseng ameliorates lipotoxicity-induced renal fibrosis in hyperuricemia mice
Magnesium 📋✍⛔38110607Dietary Magnesium Intake and Proteinuria: Is There a Relationship?
Vitamin E 📋✍⛔38290470Effect of Vitamin E on Diabetic Nephropathy: A Meta-Analysis
Metformin 📋✍⛔38345758Metformin Protects Against Acute Kidney Injury Induced by Lipopolysaccharide via Up-Regulating the MCPIP1/SIRT1 Pathway
Omega-3 Fatty Acids 📋✍⛔38464414The effects of omega-3 fatty acids supplementation on hemoglobin, hematocrit, and platelet levels of patients with ESRD condition undergoing dialysis
Thymoquinone 📋 ⛔38715182Thymoquinone: An Effective Natural Compound for Kidney Protection
Grape Seed extract 📋✍⛔36686673Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease
Apigenin 📋✍⛔38718656Boswellic acid and apigenin alleviate methotrexate-provoked renal and hippocampal alterations in rats: Targeting autophagy, NOD-2/NF-κB/NLRP3, and connexin-43
EGCG 📋✍⛔38061137The inhibitory effects of epigallocatechin-3-gallate on calcium oxalate monohydrate crystal growth, aggregation and crystal-cell adhesion
Astaxanthin 📋✍⛔38720817Ameliorative impacts of astaxanthin against atrazine-induced renal toxicity through the modulation of ionic homeostasis and Nrf2 signaling pathways in mice
L-Carnitine 📋✍⛔38322874Protective effects of l-carnitine on isoprenaline -induced heart and kidney dysfunctions: Modulation of inflammation and oxidative stress-related gene expression in rats
Silymarin 📋✍⛔38700358Therapeutic Potential of Silymarin in Mitigating Paclitaxel-Induced Hepatotoxicity and Nephrotoxicity: Insights into Oxidative Stress, Inflammation, and Apoptosis in Rats
Naringenin 📋✍⛔38345349NARINGENIN'S EFFECTS ON DIURESIS AND PREVENTION OF UROLITHIASIS IN HYPERTENSIVE RATS
CoQ10 📋✍⛔38716935Protective effect of coenzyme Q10 in cyclophosphamide-induced kidney damage in rats
Fucoidan 📋✍⛔38635872Fucoidan Improves Early Stage Diabetic Nephropathy via the Gut Microbiota-Mitochondria Axis in High-Fat Diet-Induced Diabetic Mice
Lycopene 📋✍⛔38584465Lycopene from tomatoes and tomato products exerts renoprotective effects by ameliorating oxidative stress, apoptosis, pyroptosis, fibrosis, and inflammatory injury in calcium oxalate nephrolithiasis: the underlying mechanisms
Cordyceps 📋✍⛔38517396Cordyceps sinensis extract protects against acute kidney injury by inhibiting perforin expression in NK cells via the STING/IRF3 pathway
Crocin 📋✍⛔38662441Crocin, the compound of the dried stigma of Crocus sativus L (saffron), restores doxorubicin-induced disturbances in kidney functioning, oxidative stress, inflammation, renal tissue morphology and TGF-β signalling pathways
Luteolin 📋✍⛔36362919An In-Silico Identification of Potential Flavonoids against Kidney Fibrosis Targeting TGFβR-1
Puerarin 📋✍⛔38308547Inhibition of Pyroptosis of Renal Tubular Epithelial Cells by Puerarin via Regulation of lncRNA NEAT1 Ameliorating Chronic Renal Failure
Salvianolic Acid 📋 38070193Salvianolic acid B attenuates diabetic nephropathy through alleviating ADORA2B, NALP3 inflammasome, and NFκB activity
Salidroside 📋 38259279Pharmacological functions of salidroside in renal diseases: facts and perspectives
Ellagic Acid 📋✍⛔38465322Renal protection by ellagic acid in a rat model of glycerol-induced acute kidney injury
Hesperidin 📋✍⛔38548778Cyclosporine-induced kidney damage was halted by sitagliptin and hesperidin via increasing Nrf2 and suppressing TNF-α, NF-κB, and Bax
Sulforaphane 📋✍⛔38141891Sulforaphane protects from kidney damage during the release of unilateral ureteral obstruction (RUUO) by activating nuclear factor erythroid 2-related factor 2 (Nrf2): Role of antioxidant, anti-inflammatory, and antiapoptotic mechanisms
Ginkgo Biloba 📋✍⛔37087791Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells
Icariin 📋✍ 38583082Icariin alleviates renal inflammation and tubulointerstitial fibrosis via Nrf2-mediated attenuation of mitochondrial damage
Mangiferin 📋 ⛔38094010Mangiferin alleviates renal inflammatory injury in spontaneously hypertensive rats by inhibiting MCP-1/CCR2 signaling pathway
Allicin 📋✍⛔37830900Allicin Alleviates Mitochondrial Dysfunction in Acrylamide-Induced Rat Kidney Involving the Regulation of SIRT1
Baicalin 📋✍⛔38132855Baicalin Exhibits a Protective Effect against Cisplatin-Induced Cytotoxic Damage in Canine Renal Tubular Epithelial Cells
Moringa Oleifera 📋✍⛔36584917Moringa oleifera impedes protein glycation and exerts reno-protective effects in streptozotocin-induced diabetic rats
Selenium 📋✍⛔38432121Selenium protects against Pb-induced renal oxidative injury in weaning rats and human renal tubular epithelial cells through activating NRF2
Angelica 📋✍⛔38404557The effect of Astragali Radix-Radix Angelica Sinensis on acute kidney injury: a network pharmacology and molecular docking study
Diosmin 📋✍⛔38195573Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation
Lipoic Acid 📋✍⛔37378741Antioxidant and Anti-inflammatory Effects of α-Lipoic Acid on Lipopolysaccharide-induced Oxidative Stress in Rat Kidney
Rutin 📋✍⛔38479315Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation
Tanshinone 📋 38650121Tanshinone IIA suppresses ferroptosis to attenuate renal podocyte injury in diabetic nephropathy through the embryonic lethal abnormal visual-like protein 1 and acyl-coenzyme A synthetase long-chain family member 4 signaling pathway
TUDCA 📋✍⛔38518722Exploring the impact of high-altitude de-acclimatization on renal function: The roles of oxidative and endoplasmic reticulum stress in rat models
Emodin 📋 ⛔37552124Emodin attenuate diabetic kidney disease by inhibiting ferroptosis via up regulating Nrf2 expression
Fisetin 📋✍⛔38426151Fisetin enhances cisplatin sensitivity in renal cell carcinoma via the CDK6/PI3K/Akt/mTOR signaling pathway
Gallic Acid 📋 ⛔38158692Gallic acid alleviates lipopolysaccharide-induced renal injury in rats by inhibiting cell pro-death and inflammatory response and its mechanism
Pterostilbene 📋✍⛔37566321Protective potential of pterostilbene against cyclophosphamide-induced nephrotoxicity and cystitis in rats
Zinc 📋✍⛔36996303Zinc Deficiency: A Potential Hidden Driver of the Detrimental Cycle of Chronic Kidney Disease and Hypertension
Chrysin 📋✍⛔37716503Chrysin attenuates paclitaxel-induced hepatorenal toxicity in rats by suppressing oxidative damage, inflammation, and apoptosis
Asiatic Acid 📋 37413899Asiatic acid alleviates cisplatin-induced renal fibrosis in tumor-bearing mice by improving the TFEB-mediated autophagy-lysosome pathway
Kaempferol 📋✍⛔37440431Kaempferol improves acute kidney injury via inhibition of macrophage infiltration in septic mice
Red Sage 📋✍⛔38380573Effect and pharmacological mechanism of Salvia miltiorrhiza and its characteristic extracts on diabetic nephropathy
Genistein 📋✍⛔36932924Genistein attenuates renal ischemia-reperfusion injury via ADORA2A pathway
Naringin 📋✍⛔38037725Naringin attenuates oxaliplatin-induced nephrotoxicity and hepatotoxicity: A molecular, biochemical, and histopathological approach in a rat model
NMN 📋✍⛔35962139Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN/NAD consumers mediated by Twist2
Nobiletin 📋✍ 38563051Nobiletin alleviates methotrexate-induced hepatorenal toxicity in rats
Tribulus Terrestris 📋✍⛔38716323Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial
L-Carnosine 📋✍⛔38081616[Carnosine protects against diabetic nephropathy in rats by activating the AKT/mTOR pathway and restoring autophagy in the renal tissue]
Silibinin 📋✍ 38136238Silibinin Inhibits Cell Ferroptosis and Ferroptosis-Related Tissue Injuries
Vitamin K 📋✍⛔36138326Dysbiosis in Patients with Chronic Kidney Disease: Let Us Talk About Vitamin K
Caffeine 📋✍⛔37799542Caffeine causes cell cycle arrest at G0/G1 and increases of ubiquitinated proteins, ATP and mitochondrial membrane potential in renal cells
Galangin 📋 35687907Cardiorenal dysfunction and hypertrophy induced by renal artery occlusion are normalized by galangin treatment in rats
Medicinal Plants 📋 37742600Therapeutic application of traditional Chinese medicine in kidney disease: Sirtuins as potential targets
Olive Oil 📋✍⛔37673343The potential protectivity of honey and olive oil in methotrexate induced renal damage in rats
Reishi Mushrooms 📋✍⛔37841924Therapeutic potential of Ganoderma lucidum polysaccharide peptide in Doxorubicin-induced nephropathy: modulation of renin-angiotensin system and proteinuria
Acai Berry 📋✍⛔36460743Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities in renal tubular cells and mice with kidney failure
Bee Propolis 📋✍⛔38419887Propolis and its therapeutic effects on renal diseases: A review
Carvacrol 📋✍⛔38256015Oregano ( Origanum vulgare) Essential Oil and Its Constituents Prevent Rat Kidney Tissue Injury and Inflammation Induced by a High Dose of L-Arginine
Coffee 📋✍⛔38160137Coffee consumption and risk of kidney function decline in a Dutch population-based cohort
Ferulic Acid 📋✍⛔37724953Renoprotective effects of ferulic acid mediated by AMPKα1 against lipopolysaccharide-induced damage
Food 📋 37935200Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD-a randomized controlled trial
Formononetin 📋 36586573Formononetin ameliorates ferroptosis-associated fibrosis in renal tubular epithelial cells and in mice with chronic kidney disease by suppressing the Smad3/ATF3/SLC7A11 signaling
Goji Berry 📋✍⛔37722516Intervention effect of Lycium barbarum polysaccharide on lead-induced kidney injury mice and its mechanism: A study based on the PI3K/Akt/mTOR signaling pathway
Gotu Kola 📋✍⛔34326888Ethanolic Extract of Centella asiatica Treatment in the Early Stage of Hyperglycemia Condition Inhibits Glomerular Injury and Vascular Remodeling in Diabetic Rat Model
Honokiol 📋 37898101A novel combination therapy with Cabozantinib and Honokiol effectively inhibits c-Met-Nrf2-induced renal tumor growth through increased oxidative stress
Micronutrients 📋 ⛔38474096Therapeutic Effect of Natural Products and Dietary Supplements on Aflatoxin-Induced Nephropathy
Ollive Leaf extract 📋✍⛔37497380Ameliorative Effect of Olea europaea Leaf Extract on Cisplatin-Induced Nephrotoxicity in the Rat Model
Pomegranate 📋 ⛔38027401Possible role of pomegranate fruit in reversing renal damage in rats exposed to Phenylhydrazine
Catalpol 📋 38325797Catalpol ameliorates fructose-induced renal inflammation by inhibiting TLR4/MyD88 signaling and uric acid reabsorption
Cornus 📋 38278375Cornus officinalis var. koreana Kitam extracts alleviate cadmium-induced renal fibrosis by targeting matrix metallopeptidase 9
Eicosapentaenoic Acid 📋✍⛔34977254Protective Effects of Eicosapentaenoic Acid on the Glomerular Endothelium via Inhibition of EndMT in Diabetes
Modified Citrus Pectin 📋✍⛔38588017Modified Citrus Pectin (MCP) Confers a Renoprotective Effect on Early-Stage Nephropathy in Type-2 Diabetic Mice
Oleuropein 📋 38582273Oleuropein attenuates the nephrotoxic effect of sunitinib in rats: Unraveling the potential role of SIRT6/Notch-1/NLRP-3/IL-1β axis
Phytochemicals 📋 37569752Diabetic Nephropathy: Significance of Determining Oxidative Stress and Opportunities for Antioxidant Therapies
Rosmarinic Acid 📋✍ 38376274Protective effect of rosmarinic acid on the transmembrane transporter Ctr1 expression in cisplatin-treated mice
Tea 📋 38428885Impact of habitual intake of glucosamine, fresh fruit, and tea on the risk of urolithiasis: A two-sample Mendelian randomization study
Telmisartan 📋 ⛔38074815Telmisartan combined with calcitriol enhances therapeutic efficacy for diabetic nephropathy while inhibiting inflammation and renal interstitial fibrosis
Vitamin B9 📋✍⛔38326739Impact of folic acid supplementation on ischemia‒reperfusion-induced kidney injury in rats: folic acid prophylactic role revisited
Amygdalin 📋✍⛔34278886Metabolomics reveals the renoprotective effect of n-butanol extract and amygdalin extract from Amygdalus mongolica in rats with renal fibrosis
Arctigenin 📋 38215692Additive renal protective effects between arctigenin and puerarin in diabetic kidney disease
Butyrate 📋 ⛔38358014Sodium butyrate ameliorated diabetic nephropathy-associated tubulointerstitial inflammation by modulating the tight junctions of renal tubular epithelial cells
Capsaicin 📋✍⛔38255865Spice Up Your Kidney: A Review on the Effects of Capsaicin in Renal Physiology and Disease
Date 📋 ⛔38529813Water-soluble phenolics from Phoenix dactylifera fruits as potential reno-protective agent against cisplatin-induced toxicity: pre- and post-treatment strategies
Dihydromyricetin 📋✍⛔38035992Dihydromyricetin protects against gentamicin-induced nephrotoxicity via upregulation of renal SIRT3 and PAX2
Dihydroquercetin 📋 36769524Renoprotective Effect of Taxifolin in Paracetamol-Induced Nephrotoxicity: Emerging Evidence from an Animal Model
Fish Oil 📋✍⛔38065716Habitual fish oil supplementation, genetic susceptibility of kidney stones and the risk of new-onset kidney stones
Fucoxanthin 📋✍⛔35126819Fucoxanthin Attenuates Oxidative Damage by Activating the Sirt1/Nrf2/HO-1 Signaling Pathway to Protect the Kidney from Ischemia-Reperfusion Injury
Gingerol 📋✍ 35728306Protective effects and possible mechanism of 6-gingerol against arsenic trioxide-induced nephrotoxicity based on network pharmacological analysis and experimental validation
Hesperetin 📋 36985731Antioxidant, Antiapoptotic, and Anti-Inflammatory Effects of Hesperetin in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury
Indian Gooseberry 📋 ⛔36034880Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid
L-Glutamine 📋✍⛔37851784L-glutamine supplementation reduced morphological damage in the renal glomerulus of rats with Walker-256 tumor
Paeoniflorin 📋 37884904Paeoniflorin alleviates hypoxia/reoxygenation injury in HK-2 cells by inhibiting apoptosis and repressing oxidative damage via Keap1/Nrf2/HO-1 pathway
Rhubarb 📋 ⛔38340950Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways
Roselle 📋✍⛔38708257Nephroprotective Effect of Hibiscus Sabdariffa Leaf Flavonoid Extracts via KIM-1 and TGF-1β Signaling Pathways in Streptozotocin-Induced Rats
Aged Garlic 📋✍⛔35366767S-Allylcysteine (SAC) Exerts Renoprotective Effects via Regulation of TGF- β1/Smad3 Pathway Mediated Matrix Remodeling in Chronic Renal Failure
Bee Venom 📋✍⛔38584815Melittin induces autophagy to alleviate chronic renal failure in 5/6-nephrectomized rats and angiotensin II-induced damage in podocytes
Betulinic Acid 📋 37631096Protective Role of Betulinic Acid against Cisplatin-Induced Nephrotoxicity and Its Antibacterial Potential toward Uropathogenic Bacteria
Docosahexaenoic Acid 📋✍⛔36875087Lipidome modulation by dietary omega-3 polyunsaturated fatty acid supplementation or selective soluble epoxide hydrolase inhibition suppresses rough LPS-accelerated glomerulonephritis in lupus-prone mice
Green Tea 📋✍⛔36434069Green tea and coffee consumption and risk of kidney cancer in Japanese adults
Green Tea Polyphenols 📋✍⛔37734331Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice
Hyperoside 📋 37885225Hyperoside ameliorates cisplatin-induced acute kidney injury by regulating the expression and function of Oat1
Licorice Root 📋✍⛔36474572Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo
NAD 📋 37592796NAD+ Protects Against Hyperlipidemia‑induced Kidney Injury in Apolipoprotein E‑deficient Mice
Pomegranate Peel extract 📋✍⛔38213945Methanol Crude Peel Extract of P. granatum Prevents Oxidative Damage in Kidneys of Rats Exposed to Highly Active Antiretroviral Therapy
Probiotics 📋✍⛔38558739Exploring the Impact of Optimized Probiotic Supplementation Techniques on Diabetic Nephropathy: Mechanisms and Therapeutic Potential
Rehmannia 📋✍⛔37579922Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple ameliorates renal interstitial fibrosis in CKD rats by inhibiting the TGF-β1/MAPK signaling pathway
Tangeretin 📋 37354638Connexin43 is associated with the progression of clear cell renal carcinoma and is regulated by tangeretin to sygergize with tyrosine kinase inhibitors
Taurine 📋✍⛔37805666The renoprotective effects of taurine against diabetic nephropathy via the p38 MAPK and TGF-β/Smad2/3 signaling pathways
Wogonin 📋✍⛔34295152Wogonin Alleviates Kidney Tubular Epithelial Injury in Diabetic Nephropathy by Inhibiting PI3K/Akt/NF-κB Signaling Pathways
Andrographolide 📋 38478853Andrographolide attenuates sepsis-induced acute kidney injury by inhibiting ferroptosis through the Nrf2/FSP1 pathway
Baicalein 📋✍⛔38601597Baicalein improves renal interstitial fibrosis by inhibiting the ferroptosis in vivo and in vitro
Cranberry 📋✍⛔38529450Potential of Cranberry Jelly to Prevent Urinary Stone Formation After Cutaneous Ureterostomy: A Case Report
Diosgenin 📋 37630743Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics
Geraniol 📋 38362098The Inhibitory Effect of Geraniol on CCL4-induced Hepatorenal Toxicity in Pregnant Mice through the PI3K/AKT Signaling Pathway
Ginger extract 📋✍⛔37174437Protective Effect of Quercetin and Ginger ( Zingiber officinale) Extract against Dimethoate Potentiated Fluoride-Induced Nephrotoxicity in Rats
Linalool 📋 ⛔38294506Monoterpene linalool restrains gentamicin-mediated acute kidney injury in rats by subsiding oxidative stress, apoptosis, and the NF-κB/iNOS/TNF-α/IL-1β pathway and regulating TGF-β
Nicotinamide 📋✍⛔38446387Nicotinamide protects against diabetic kidney disease through regulation of Sirt1
Pine Bark 📋✍⛔35916821Effect of pycnogenol on ethanol-related oxidative retinal injury: an experimental study
Polydatin 📋✍ 37793278Polydatin protects against calcium oxalate crystal-induced renal injury through the cytoplasmic/mitochondrial reactive oxygen species-NLRP3 inflammasome pathway
Pomegranate Seed extract 📋 ⛔38065332Pomegranate Seed Oil Mitigates Liver and Kidney Damage in an Experimental Colitis Model: Modulation of NF-κB Activation and Apoptosis
PQQ 📋✍⛔35489281Pyrroloquinoline quinone ameliorates renal fibrosis in diabetic nephropathy by inhibiting the pyroptosis pathway in C57BL/6 mice and human kidney 2 cells
Rice 📋 ⛔36379906Resistant starch from black rice, Oryza sativa L. var. ameliorates renal inflammation, fibrosis and injury in insulin resistant rats
Saffron 📋✍⛔35656071Saffron nephroprotective effects against medications and toxins: A review of preclinical data
Schisandrins 📋 38382281Schisandrin A alleviates renal fibrosis by inhibiting PKCβ and oxidative stress
Scutellarin 📋 38656633Scutellarin ameliorates diabetic nephropathy via TGF-β1 signaling pathway
Star Fuit 📋 ⛔319724232-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from the root of Averrhoa carambola L., protects against diabetic kidney disease by inhibiting TLR4/TGFβ signaling pathway
Stinging Nettle 📋✍⛔38716323Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial
Vitamin A 📋✍⛔37463986Retinol intake is associated with the risk of chronic kidney disease in individuals with type 2 diabetes mellitus: results from NHANES
Vitamin B6 📋✍⛔38691102Renal protective effect and clinical analysis of vitamin B6 in patients with sepsis
Zingerone 📋 36822304Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes
Andrographis 📋✍⛔35196932Andrographis paniculata mitigates first-line anti-tubercular drugs-induced nephrotoxicity in Wistar rats
Anthocyanins 📋✍⛔36335368Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism
Artemisinin 📋 37309415Exploration of Artemisinin Against IgA Nephropathy via AKT/Nrf2 Pathway by Bioinformatics and Experimental Validation
Barberry 📋✍⛔35427583Berberis integerrima hydro-alcoholic root extract ant its constituent berberine protect against cisplatin-induced nephro- and hepato-toxicity
Boric Acid 📋✍⛔37562273Therapeutic role of boron on acrylamide-induced nephrotoxicity, cardiotoxicity, neurotoxicity, and testicular toxicity in rats: Effects on Nrf2/Keap-1 signaling pathway and oxidative stress
Calycosin 📋 36278223Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway
Carnosic Acid 📋 34946671Protective Effects of Carnosic Acid on Lipopolysaccharide-Induced Acute Kidney Injury in Mice
Catechins 📋 38687305(+)-Catechin ameliorates diabetic nephropathy injury by inhibiting endoplasmic reticulum stress-related NLRP3-mediated inflammation
Chlorogenic Acid 📋✍⛔38501417[Chlorogenic acid alleviates acute kidney injury in septic mice by inhibiting NLRP3 inflammasomes and the caspase-1 canonical pyroptosis pathway]
Chokeberry 📋✍⛔37511414The Protective Potential of Aronia melanocarpa L. Berry Extract against Cadmium-Induced Kidney Damage: A Study in an Animal Model of Human Environmental Exposure to This Toxic Element
Dandelion 📋✍⛔34532027Dandelion sterol improves diabetes mellitus-induced renal injury in in vitro and in vivo study
Dioscin 📋 36960871Mechanism of dioscin ameliorating renal fibrosis through NF‑κB signaling pathway‑mediated inflammatory response
Ginkgolides 📋 37715308Ginkgolide A downregulates transient receptor potential (melastatin) 2 to protect cisplatin-induced acute kidney injury in rats through the TWEAK/Fn14 pathway: Ginkgolide A improve acute renal injury
Glycyrrhizic Acid 📋✍⛔37648177The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway
Grape 📋 ⛔35046823Proanthocyanidins Protect Against Cadmium-Induced Diabetic Nephropathy Through p38 MAPK and Keap1/Nrf2 Signaling Pathways
Hydroxytyrosol 📋 37699441Modulation of mi-RNA25/Ox-LDL/NOX4 signaling pathway by polyphenolic compound Hydroxytyrosol as a new avenue to alleviate cisplatin-induced acute kidney injury, a mechanistic study in rats
Inulin 📋✍⛔38725443Inulin Reduces Kidney Damage in Type 2 Diabetic Mice by Decreasing Inflammation and Serum Metabolomics
Mangosteen 📋✍⛔34316206Ameliorative effect of Mangosteen ( Garcinia mangostana L.) peel infusion on the histopathological structures of the liver and kidney of rats ( Rattus norvegicus Berkenhout, 1769) after H 2 O 2 induction
Mulberry 📋 ⛔37732507Mulberry leaf extract and neochlorogenic acid ameliorate glucolipotoxicity-induced diabetic nephropathy in high-fat diet-fed db/db mice
Myricetin 📋 ⛔38313853Myricetin induces M2 macrophage polarization to alleviate renal tubulointerstitial fibrosis in diabetic nephropathy via PI3K/Akt pathway
Neferine 📋 38658442Neferine alleviates acute kidney injury by regulating the PPAR-α/NF-κB pathway
Polyphenols 📋 37635982Regulation of autophagy by natural polyphenols in the treatment of diabetic kidney disease: therapeutic potential and mechanism
Spirulina 📋✍⛔35237421The protective impacts of Spirulina platensis against cisplatin-induced renal injury through the regulation of oxidative stress, pro-inflammatory cytokines and Bax/Bcl2
Tannic Acid 📋✍⛔38393487Cyto and Genoprotective Potential of Tannic Acid Against Cadmium and Nickel Co-exposure Induced Hepato-Renal Toxicity in BALB/c Mice
Tetrahydrocurcumin 📋✍ 34474516Tetrahydrocurcumin Ameliorates Kidney Injury and High Systolic Blood Pressure in High-Fat Diet-Induced Type 2 Diabetic Mice
Argan Oil 📋✍⛔33114212The Antioxidant, Anti-Apoptotic, and Proliferative Potency of Argan Oil against Betamethasone-Induced Oxidative Renal Damage in Rats
Arjuna 📋✍⛔33743558Terminalia arjuna supplementation ameliorates high fat diet-induced oxidative stress in nephrotoxic rats
Ashwagandha 📋✍⛔37663806Protective impacts of Withania somnifera leaf extract from Taif area against diclofenac induced hepato-renal toxicity: role of antioxidants, inflammation, apoptosis, and anti-oxidative stress biomarkers
Betaine 📋✍⛔38713257Modulation of the Nrf-2 and HO-1 signalling axis is associated with Betaine's abatement of fluoride-induced hepatorenal toxicities in rats
Boswellic Acid 📋✍⛔38718656Boswellic acid and apigenin alleviate methotrexate-provoked renal and hippocampal alterations in rats: Targeting autophagy, NOD-2/NF-κB/NLRP3, and connexin-43
Cardamonin 📋 38585526Cardamonin mitigates kidney injury by modulating inflammation, oxidative stress, and apoptotic signaling in rats subjected to renal ischemia and reperfusion
Cinnamaldehyde 📋 37839279Cytoprotective effects of cinnamaldehyde and adipoRon against cyclophosphamide-induced cardio-renal toxicity in rats: Insights into oxidative stress, inflammation, and apoptosis
Cinnamon 📋✍⛔36747357Cinnamon: an aromatic condiment applicable to chronic kidney disease
Coconut Oil 📋 ⛔32523886Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats
Corn Silk 📋✍⛔38716323Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial
Daidzein 📋✍⛔37378389The effect of daidzein on renal injury in ovariectomized rats: interaction of angiotensin receptors and long non-coding RNAs H19, GAS5, MIAT, and Rian
DHEA 📋✍⛔35784547Low Serum Dehydroepiandrosterone Is Associated With Diabetic Kidney Disease in Men With Type 2 Diabetes Mellitus
Diallyl Disulfide 📋 34084059Ameliorative Role of Diallyl Disulfide Against Glycerol-induced Nephrotoxicity in Rats
Echinacea 📋✍⛔38467789Immuno-antioxidative reno-modulatory effectiveness of Echinacea purpurea extract against bifenthrin-induced renal poisoning
Fenugreek 📋✍⛔35878267Fenugreek Seed Galactomannan Aqueous and Extract Protects against Diabetic Nephropathy and Liver Damage by Targeting NF-κB and Keap1/Nrf2 Axis
Flavonoids 📋 ⛔37200367Comprehensive in silico analyses of flavonoids elucidating the drug properties against kidney disease by targeting AIM2
Frankincense 📋✍⛔37334022Effects of frankincense on experimentally induced renal stones in rats
Geniposide 📋 38508092Geniposide reduced oxidative stress-induced apoptosis in HK-2 cell through PI3K/AKT3/FOXO1 by m6A modification
Irisin 📋 38218331The role of irisin in kidney diseases
Isoliquiritigenin 📋 37561086Isoliquiritigenin pretreatment regulates ER stress and attenuates cisplatin-induced nephrotoxicity in male Wistar rats
Knotweed 📋✍⛔37657770Polygonum cuspidatum Sieb. et Zucc. Extracts improve sepsis-associated acute kidney injury by inhibiting NF-κB-mediated inflammation and pyroptosis
L-Arginine 📋✍⛔37450015Cannabinoid receptor 2 (CB2) agonists and L-arginine ameliorate diabetic nephropathy in rats by suppressing inflammation and fibrosis through NF-κβ pathway
Lemon 📋 ⛔37692132Effects of lemon-tomato juice consumption on crystal formation in the urine of patients with calcium oxalate stones: A randomized crossover clinical trial
Licochalcones 📋 36840005Licochalcone A Suppresses Renal Cancer Cell Proliferation and Metastasis by Engagement of Sp1-Mediated LC3 Expression
Nicotinamide Riboside 📋✍⛔38464264Nicotinamide riboside activates renal metabolism and protects the kidney in a model of Alport syndrome
Oleanolic Acid 📋 38668524Oleanolic Acid Acetate Alleviates Cisplatin-Induced Nephrotoxicity via Inhibition of Apoptosis and Necroptosis In Vitro and In Vivo
Onion 📋✍⛔37928042The protective effect of allium cepa against ethylene glycol-induced kidney stones in rats
Phloretin 📋 37722590Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: A potential therapeutic approach targeting TLR4-induced inflammation
Piperine 📋✍⛔33134133Protective effect of piperine in ischemia-reperfusion induced acute kidney injury through inhibition of inflammation and oxidative stress
Poria Mushrooms 📋✍ 31452866Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum
Punicalagin 📋✍⛔34989745Punicalagin alleviates renal injury via the gut-kidney axis in high-fat diet-induced diabetic mice
Royal Jelly 📋✍⛔38476622Royal Jelly, A Super Food, Protects Against Celecoxib-Induced Renal Toxicity in Adult Male Albino Rats
Schisandra 📋✍⛔36280016Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis mixture on diabetic nephropathy
Shogaol 📋 34641472Protective Effects of 6-Shogaol, an Active Compound of Ginger, in a Murine Model of Cisplatin-Induced Acute Kidney Injury
St. Johns Wort 📋✍⛔33981220Hypericum perforatum L. Regulates Glutathione Redox Stress and Normalizes Ggt1/Anpep Signaling to Alleviate OVX-Induced Kidney Dysfunction
Theaflavins 📋✍ 38171247Theaflavin pretreatment ameliorates renal ischemia/reperfusion injury by attenuating apoptosis and oxidative stress in vivo and in vitro
Vitamin B Complex 📋 ⛔38413451The Protective Effects of Vitamin B Complex on Diclofenac Sodium-Induced Nephrotoxicity: The Role of NOX4/RhoA/ROCK
Vitamin B12 📋✍⛔34655350Evaluation by different mechanisms of the protective effects of vitamin B12 on methotrexate nephrotoxicity
Vitexin 📋 37891461Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation
Activated Charcoal 📋✍⛔38146721Effects of Increased Blood Flow Rate and Oral Activated Charcoal on the Severity of Uremic Pruritus: A Randomized Crossover Clinical Trial
Antioxidants 📋 ⛔37853637Association between an Antioxidant-Rich Japanese Diet and Chronic Kidney Disease: The Ohasama Study
Arctiin 📋 33118522[Arctiin antagonizes triptolide-induced renal toxicity in rats via anti-inflammatory pathway]
Asiaticoside 📋 37539103Asiaticoside ameliorates renal ischemia/reperfusion injury by promoting CD4+CD25+FOXP3+ treg cell differentiation
Asparagus 📋 ⛔37837591Renal-protective effect of Asparagus officinalis aqueous extract against lead-induced nephrotoxicity mouse model
Aspirin 📋 ⛔37838641Association of low-dose aspirin use for primary prevention with self-reported kidney stones prevalence: a cross-sectional study
Avocado Oil 📋 ⛔34832999Avocado Oil Prevents Kidney Injury and Normalizes Renal Vasodilation after Adrenergic Stimulation in Hypertensive Rats: Probable Role of Improvement in Mitochondrial Dysfunction and Oxidative Stress
Beets 📋✍⛔34613396Pink pressure: beetroot (Beta vulgaris rubra) as a possible novel medical therapy for chronic kidney disease
Bilberry 📋✍⛔32864929The Role of Vaccinium Myrtillus in the Prevention of Renal Injury in an Experimental Model of Ruptured Abdominal Aortic Aneurysm
Biochanin A 📋 37237918Biochanin A Ameliorates Nephropathy in High-Fat Diet/Streptozotocin-Induced Diabetic Rats: Effects on NF-kB/NLRP3 Axis, Pyroptosis, and Fibrosis
Caffeic Acid 📋✍⛔38102533The Hepatorenal Protective Potential of Caffeic Acid Consumption on the Arsenic-Exposed Syrian Mice
Cantaloupe 📋 ⛔38716323Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial
CAPE 📋 37588661The protective effect of caffeic acid phenethyl ester in the nephrotoxicity induced by α-cypermethrin
Carotenoids 📋✍⛔37740155Association of dietary carotenoid intake with the prevalence kidney stones among the general adult population
Chaga Mushrooms 📋✍⛔38161352Research Progress on Application of Inonotus obliquus in Diabetic Kidney Disease
Cinnamon Essential Oil 📋✍⛔33679180Renoprotective effects of cinnamon oil against APAP-Induced nephrotoxicity by ameliorating oxidative stress, apoptosis and inflammation in rats
Cocoa 📋✍⛔37324470Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice
Coptis Chinensis 📋 ⛔34114400Full composition granules of Huanglian (Rhizoma Coptidis) decrease the serum monocyte chemotactic protein-1 and connective tissue growth factor levels and inhibit kidney nuclear factor-κB expression in rats with high-fat diet-induced diabete
Cordycepin 📋 38014886Cordycepin inhibits kidney injury by regulating GSK-3β-mediated Nrf2 activation
Crocetin 📋 38057037Crocetin ameliorative effect on diabetic nephropathy in rats through a decrease in transforming growth factor-β and an increase in glyoxalase-I activity
Cyanidin 📋✍ 33551679The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice
Dihydroartemisinin 📋 38351420Dihydroartemisinin abolishes cisplatin-induced nephrotoxicity in vivo
Eucalyptol 📋 38115227Eucalyptol regulates Nrf2 and NF-kB signaling and alleviates gentamicin-induced kidney injury in rats by downregulating oxidative stress, oxidative DNA damage, inflammation, and apoptosis
Fiber 📋✍⛔38707305Association between dietary fiber intake and diabetic nephropathy among adult diabetes mellitus in the United States: A cross-sectional study
Fig 📋 ⛔32946057Synergistic effects of Ficus Carica extract and extra virgin olive oil against oxidative injury, cytokine liberation, and inflammation mediated by 5-Fluorouracil in cardiac and renal tissues of male albino rats
Folate 📋✍⛔37630806Folate Deficiency Enhanced Inflammation and Exacerbated Renal Fibrosis in High-Fat High-Fructose Diet-Fed Mice
Fruits 📋 38428885Impact of habitual intake of glucosamine, fresh fruit, and tea on the risk of urolithiasis: A two-sample Mendelian randomization study
Garlic 📋✍⛔38051214Evidential support for garlic supplements against diabetic kidney disease: a preclinical meta-analysis and systematic review
Ginger 📋✍⛔36369018Renoprotective effects of the ginger (Zingiber officinale) on Diabetic kidney disease, current knowledge and future direction: a systematic review of animal studies
Ginkgetin 📋 34148304Ginkgetin alleviates high glucose-evoked mesangial cell oxidative stress injury, inflammation, and extracellular matrix (ECM) deposition in an AMPK/mTOR-mediated autophagy axis
Glucosamine 📋✍⛔38428885Impact of habitual intake of glucosamine, fresh fruit, and tea on the risk of urolithiasis: A two-sample Mendelian randomization study
Haritaki 📋✍⛔38159820The Terminalia chebula Retz extract treats hyperuricemic nephropathy by inhibiting TLR4/MyD88/NF-κB axis
Hawthorn 📋✍⛔36076481Interval training and Crataegus persica ameliorate diabetic nephropathy via miR-126/Nrf-2 mediated inhibition of stress oxidative in rats with diabetes after myocardial ischemia-reperfusion injury
Jujube 📋 ⛔37245086Hydroalcoholic Extract of Ziziphus Jujuba Leaf to Prevent Ethylene Glycol and Ammonium Chloride-Induced Kidney Stones in Male Rat: Is it Effective?
L-Theanine 📋✍⛔36415057L-Theanine Mitigates the Harmful Effects of Excess High-Protein Diet in Rats by Regulating Protein Metabolism
Ligustilide 📋 36921687Levistolide A ameliorates fibrosis in chronic kidney disease via modulating multitarget actions in vitro and in vivo
Marjoram 📋 ⛔36723325ORIGANUM MAJORANA ATTENUATES CIPROFLOXACIN-INDUCED NEPHROPATHY IN RATS
Nootkatone 📋 36829928Nootkatone Supplementation Attenuates Carbon Tetrachloride Exposure-Induced Nephrotoxicity in Mice
Orange 📋 ⛔32466228Effects of a Red Orange and Lemon Extract in Obese Diabetic Zucker Rats: Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidase
Paeonol 📋 35185559Paeonol Protects Against Methotrexate-Induced Nephrotoxicity via Upregulation of P-gp Expression and Inhibition of TLR4/NF-κB Pathway
Parthenolide 📋 36985711Parthenolide Phytosomes Attenuated Gentamicin-Induced Nephrotoxicity in Rats via Activation of Sirt-1, Nrf2, OH-1, and NQO1 Axis
Perilla 📋✍ 37513901The Effects of Perilla frutescens Extracts on IgA Nephropathy: A Systematic Review and Meta-Analysis
Potassium 📋✍⛔37330455Low Potassium Intake: A Common Risk Factor for Nephrolithiasis in Patients with High Blood Pressure
PUFA 📋 36356379Polyunsaturated fatty acids ameliorate renal stone-induced renal tubular damage via miR-93-5p/Pknox1 axis
Rosemary 📋✍⛔32206031Nephroprotective Effect of Green Tea, Rosmarinic Acid and Rosemary on N-diethylnitrosamine Initiated and Ferric Nitrilotriacetate Promoted Acute Renal Toxicity in Wistar Rats
Rosemary Essential Oil 📋✍⛔37016650Assessment of Effects of Rosemary Essential Oil on the Kidney Pathology of Diabetic Adult Male Albino Rats
Sea Buckthorn 📋✍⛔37614189Hippophae rhamnoides L. leaf extracts alleviate diabetic nephropathy via attenuation of advanced glycation end product-induced oxidative stress in db/db mice
Soy Isoflavones 📋✍⛔34236368Effects of soy isoflavone supplementation on patients with diabetic nephropathy: a systematic review and meta-analysis of randomized controlled trials
Soy Protein 📋✍⛔37693248Comparison of the effects of different percentages of soy protein in the diet on patients with type 2 diabetic nephropathy: systematic reviews and network meta-analysis
Thymol 📋✍⛔38256015Oregano ( Origanum vulgare) Essential Oil and Its Constituents Prevent Rat Kidney Tissue Injury and Inflammation Induced by a High Dose of L-Arginine
Urolithins 📋 36010548Urolithins Modulate the Viability, Autophagy, Apoptosis, and Nephrin Turnover in Podocytes Exposed to High Glucose
Ursolic Acid 📋✍⛔37300450Ursolic acid-downregulated long noncoding RNA ASMTL-AS1 inhibits renal cell carcinoma growth via binding to HuR and reducing vascular endothelial growth factor expression
Vitamin B3 📋✍⛔35631221Association between Vitamin Intake and Chronic Kidney Disease According to a Variant Located Upstream of the PTGS1 Gene: A Cross-Sectional Analysis of Shika Study
Vitamin K1 📋✍⛔31639794Vitamin K1 Inhibition of Renal Crystal Formation through Matrix Gla Protein in the Kidney
Withaferin A 📋 33007732Withaferin A protects against endoplasmic reticulum stress-associated apoptosis, inflammation, and fibrosis in the kidney of a mouse model of unilateral ureteral obstruction
Yam 📋 37856796Meta-analysis of Huangqi (Astragalus membranaceus) and Chinese Yam (Rhizoma Dioscoreae) for Diabetic Nephropathy
Acacetin 📋 32175062Acacetin Attenuates Renal Damage-Induced by Ischemia-Reperfusion with Declining Apoptosis and Oxidative Stress in Mice
Aloe Vera 📋✍⛔29621403Amelioration of Diabetes-Induced Diabetic Nephropathy by Aloe Vera: Implication of Oxidative Stress and Hyperlipidemia
Aloe-Emodin 📋 35518350Aloe-Emodin Ameliorates Diabetic Nephropathy by Targeting Interferon Regulatory Factor 4
Anethole 📋 36404830Renoprotective activity of anethole- rich fraction from aromatic herbs on junk food induced diabetic nephropathy in rats
Apple 📋 ⛔32820471Protective Effect of Grape and Apple Juices against Cadmium Intoxication in the Kidney of Rats
Apple Vinegar 📋✍⛔37090488GC-MS based metabolite profiling, antioxidant and antiurolithiatic properties of apple cider vinegar
Arachidonic Acid 📋✍⛔34940691Influence of Polyunsaturated Fatty Acid Intake on Kidney Functions of Rats with Chronic Renal Failure
Astragalin 📋 36859596Astragalin ameliorates renal injury in diabetic mice by modulating mitochondrial quality control via AMPK-dependent PGC1α pathway
Bacopa Monnieri 📋✍⛔27784187Renoprotective effect of Bacopa monnieri via inhibition of advanced glycation end products and oxidative stress in STZ-nicotinamide-induced diabetic nephropathy
Basil 📋✍⛔38150214Antioxidant and Protective Effect of Ocimum basilicum Seeds Extract on Renal Toxicity Induced by Carbon Tetrachloride in Rats
Bee Pollen 📋✍⛔35589738Protective effect of bee pollen in acute kidney injury, proteinuria, and crystalluria induced by ethylene glycol ingestion in rats
Beta-Glucan 📋✍⛔38444353β-Glucan ameliorates cisplatin-induced oxidative and histological damage in kidney and liver of rats
Beta-Sitosterol 📋✍⛔33048170The targets of β-sitosterol as a novel therapeutic against cardio-renal complications in acute renal ischemia/reperfusion damage
Blackcurrant 📋✍⛔34601083Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells
Brazil Nut 📋 ⛔30118536Inflammation and kidney injury attenuated by prior intake of Brazil nuts in the process of ischemia and reperfusion
Bromelain 📋✍⛔34630950Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease
Buckwheat 📋 ⛔37150497Tartary buckwheat flavonoids alleviates high-fat diet induced kidney fibrosis in mice by inhibiting MAPK and TGF-β1/Smad signaling pathway
Cabbage 📋 ⛔37580924Study of ameliorative effect of Allium cepa essential oil and purple cabbage (Brassica Oleracea Var. Capitata F. Rubra) leaves extract on CCl4 induced nephrotoxicity in rats
Calcium 📋✍⛔35933132Dietary Risk Factors for Incident and Recurrent Symptomatic Kidney Stones
Cannabidiol 📋✍⛔29897289Impact of Cannabidiol Treatment on Regulatory T-17 Cells and Neutrophil Polarization in Acute Kidney Injury
Carrot 📋 ⛔34949157The nephroprotective effects of Daucus carota and Eclipta prostrata against cisplatin-induced nephrotoxicity in rats
Chamomile Essential Oil 📋✍⛔27912887Nephroprotective effects of (-)-α-bisabolol against ischemic-reperfusion acute kidney injury
Chlorella 📋✍⛔38704764Therapeutic potential of Lactobacillus casei and Chlorella vulgaris in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD)-associated kidney damages: a stereological study
Choline 📋✍⛔36519607Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats
Chrysanthemum 📋✍⛔35355712An Optimized Two-Herb Chinese Food as Medicine Formula Reduces Cisplatin-Induced Nephrotoxicity in the Treatment of Lung Cancer in Mice
Citicoline 📋✍⛔36519607Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats
Citrus Fruits 📋 ⛔36658686Citrus fruit intake and incidence of renal cell carcinoma: A meta-analysis of observational studies
Coconut 📋 ⛔37975366Oral administration of naringenin and a mixture of coconut water and Arabic gum attenuate oxidative stress and lipid peroxidation in gentamicin-induced nephrotoxicity in rats
Coriander 📋 ⛔30845182Coriandrum sativum seeds extract mitigate progression of diabetic nephropathy in experimental rats via AGEs inhibition
Cryptotanshinone 📋 35132325Cryptotanshinone Suppressed Postmenopausal Osteoporosis by Preventing RANKL-Mediated Osteoclastogenesis against Kidney Injury
Diallyl Trisulfide 📋 38128310Diallyl trisulfide and its active metabolite allyl methyl sulfone attenuate cisplatin-induced nephrotoxicity by inhibiting the ROS/MAPK/NF-κB pathway
Diosmetin 📋 35119062Diosmin, a citrus fruit-derived phlebotonic bioflavonoid protects rats from chronic kidney disease-induced loss of bone mass and strength without deteriorating the renal function
Eucommia 📋✍⛔37517819Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro
Eugenol 📋 36113730Nephroprotective potential of eugenol in a rat experimental model of chronic kidney injury; targeting NOX, TGF-β, and Akt signaling
Evening Primrose Oil 📋✍⛔23074118Gamma linolenic acid exerts anti-inflammatory and anti-fibrotic effects in diabetic nephropathy
Flaxseed 📋✍⛔34665824Effect of flaxseed on systemic inflammation and oxidative stress in diabetic rats with or without chronic kidney disease
GABA 📋✍⛔35714569GABA alleviates high glucose-induced podocyte injury through dynamically altering the expression of macrophage M1/M2-derived exosomal miR-21a-5p/miR-25-3p
Ganoderic Acid 📋 34638569Ganoderic Acids Prevent Renal Ischemia Reperfusion Injury by Inhibiting Inflammation and Apoptosis
Glycyrrhetinic Acid 📋 38222784Potential therapeutic targets for the prevention of diabetic nephropathy: Glycyrrhetinic acid
Guggulsterone 📋 35123992Z-Guggulsterone alleviates renal fibrosis by mitigating G2/M cycle arrest through Klotho/p53 signaling
Honey 📋✍⛔37673343The potential protectivity of honey and olive oil in methotrexate induced renal damage in rats
Isorhamnetin 📋 38466121Isorhamnetin ameliorates cisplatin-induced acute kidney injury in mice by activating SLPI-mediated anti-inflammatory effect in macrophage
Kudzu Root 📋✍⛔34514791Metabolic Profiling of Carbonyl Compounds for Unveiling Protective Mechanisms of Pueraria lobata against Diabetic Nephropathy by UPLC-Q-Orbitrap HRMS/MS Analysis
L-Histidine 📋✍⛔33513395Protective effect of oral histidine on hypertension in Dahl salt-sensitive rats induced by high-salt diet
Limonin 📋 37741252Limonin mitigates cisplatin-induced acute kidney injury through metabolic reprogramming
Liquiritigenin 📋 35744945Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function
Lotus 📋 ⛔36501396In Vitro and In Vivo Nephroprotective Effects of Nelumbo nucifera Seedpod Extract against Cisplatin-Induced Renal Injury
Lutein 📋✍⛔37755751Lutein Modulates Oxidative Stress, Inflammatory and Apoptotic Biomarkers Related to Di-(2-Ethylhexyl) Phthalate (DEHP) Hepato-Nephrotoxicity in Male Rats: Role of Nuclear Factor Kappa B
Maitake Mushrooms 📋 ⛔35616773Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway
Marigold 📋✍⛔34229058Tagetes erecta L. flowers, a medicinal plant traditionally used to promote diuresis, induced diuretic and natriuretic effects in normotensive and hypertensive rats
Matcha Tea 📋 38647648Comparative study of the anti-inflammatory activity of etoricoxib and Matcha green tea against acute kidney injury induced by gamma radiation in rats
Milk Thistle 📋✍⛔34630852Tackling of Renal Carcinogenesis in Wistar Rats by Silybum marianum Total Extract, Silymarin, and Silibinin via Modulation of Oxidative Stress, Apoptosis, Nrf2, PPAR γ, NF- κ B, and PI3K/Akt Signaling Pathways
Motherwort 📋✍⛔34980736Leonurine Preconditioning Attenuates Ischemic Acute Kidney Injury in Rats by Promoting Nrf2 Nuclear Translocation and Suppressing TLR4/NF-κB Pathway
Neem 📋✍ 36522378Glucosidase inhibitor, Nimbidiol ameliorates renal fibrosis and dysfunction in type-1 diabetes
Nuciferine 📋 38006352Nuciferine Protects against Obesity-Induced Nephrotoxicity through Its Hypolipidemic, Anti-Inflammatory, and Antioxidant Effects
Oregano 📋✍⛔34168532The antiurolithic activity of Origanum vulgare on rats treated with ethylene glycol and ammonium chloride: Possible pharmaco-biochemical and ultrastructure effects
Papaya 📋✍⛔37360438Mercuric Chloride Induced Nephrotoxicity: Ameliorative Effect of Carica papaya Leaves Confirmed by Histopathology, Immunohistochemistry, and Gene Expression Studies
Peas 📋 ⛔34630950Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease
Peppermint 📋✍⛔37900086The effect of nutritional factors on urolithiasis: A case-control study
Peppermint Essential Oil 📋✍⛔34836852Prophylactic and curative potential of peppermint oil against calcium oxalate kidney stones
Persimmon 📋 ⛔33522322Nephroprotective effect of persimmon leaves ( Diospyros kaki L.f.) against CCl 4-induced renal toxicity in Swiss Albino rats
Pumpkin Seed 📋✍⛔38213175Deciphering Multi-target Pharmacological Mechanism of Cucurbita pepo Seeds against Kidney Stones: Network Pharmacology and Molecular Docking Approach
Red Yeast Rice 📋✍⛔33312555An antidiabetic nutraceutical combination of red yeast rice ( Monascus purpureus), bitter gourd ( Momordica charantia), and chromium alleviates dedifferentiation of pancreatic β cells in db/db mice
Retinoic Acid 📋 33820492All-trans retinoic acid regulating angiopoietins-1 and alleviating extracellular matrix accumulation in interstitial fibrosis rats
Scutellarein 📋 34619498Scutellarein relieves the death and inflammation of tubular epithelial cells in ischemic kidney injury by degradation of COX-2 protein
Sesame Oil 📋 ⛔35532693Kidney dysfunction and oxidative stress in doxorubicin-induced nephrotic rat: Protective role of sesame oil
Sesamin 📋✍ 36232918The Protective Effects of Sesamin against Cyclophosphamide-Induced Nephrotoxicity through Modulation of Oxidative Stress, Inflammatory-Cytokines and Apoptosis in Rats
Sesamol 📋 38350822Protective Effects of Sesamol on Renal Ischemia-Reperfusion Injury Via Regulation of Nuclear Factor Erythroid 2-Related Factor 2 Pathway
Skullcap 📋✍⛔33643031The Combination of Scutellaria baicalensis Georgi and Sophora japonica L. ameliorate Renal Function by Regulating Gut Microbiota in Spontaneously Hypertensive Rats
Sodium Bicarbonate 📋✍⛔37251318Effect of sodium bicarbonate on cardiovascular outcome and mortality in patients with advanced chronic kidney disease
Soy 📋✍⛔37081921Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study
Spermidine 📋 37380734Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis
Strawberry 📋✍⛔28567583Protective Effects of Fragaria ananassa Extract Against Cadmium Chloride-Induced Acute Renal Toxicity in Rats
Syringic Acid 📋 36960519Nephroprotective potential of syringic acid in experimental diabetic nephropathy: Focus on oxidative stress and autophagy
Thyme 📋✍⛔27973970Potential Renoprotective Effects of Rosemary and Thyme Against Gentamicin Toxicity in Rats
Thyme Essential Oil 📋 ⛔36337844The Effect of Thyme Essential Oil on Liver Injuries Caused by Renal Ischemia-Reperfusion in Rats
Tongkat Ali 📋✍⛔37433989Eurycoma longifolia alkaloid components ameliorate hyperuricemic nephropathy via regulating serum uric acid level and relieving inflammatory reaction
Trehalose 📋 ⛔35463818Effects of trehalose on NFE2L2, catalase, and superoxide dismutase in the kidney of aged rats
Vitamins 📋 37391399Vitamin D deficiency contributes to the diabetic kidney disease progression via increase ZEB1/ZEB2 expressions
Walnut 📋 ⛔30666075Juglans Regia L. Leaf Extract Attenuates Diabetic Nephropathy Progression in Experimental Diabetes: An Immunohistochemical Study
Wormwood 📋✍⛔36942132Hepatorenal protective activity of Artemisia against diclofenac toxicity in male rats
Aloin 📋 31254592Renal protective effects of aloin in a mouse model of sepsis
Alpha-Linolenic Acid 📋✍⛔38039041Alpha-linolenic acid protects against methotrexate-induced nephrotoxicity in mouse kidney cells
Anise 📋✍⛔27860049Pimpinella anisum L. ethanolic extract ameliorates the gentamicin- induced nephrotoxicity in rats
Anthocyanidins 📋 36900199Dietary Intake of Anthocyanidins and Renal Cancer Risk: A Prospective Study
Apricot Kernels 📋✍⛔26781971Amygdalin Blocks the in Vitro Adhesion and Invasion of Renal Cell Carcinoma Cells by an Integrin-Dependent Mechanism
Artichoke 📋✍⛔38031637Protective effect of chicory and/or artichoke leaves extracts on carbon tetrachloride and gamma-irradiation-induced chronic nephrotoxicity in rats
Avocado 📋✍⛔34365580Nephroprotective and anti-inflammatory potential of aqueous extract from Persea americana seeds against cadmium-induced nephrotoxicity in Wistar rats
Balloon Flower 📋✍⛔37146841Platycodin D inhibits HFD/STZ-induced diabetic nephropathy via inflammatory and apoptotic signaling pathways in C57BL/6 mice
BCAA 📋✍⛔32845566Regular exercise and branched-chain amino acids prevent ischemic acute kidney injury-related muscle wasting in mice
Bean 📋 ⛔37081921Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study
Bergamot 📋✍⛔30884780Oxidative Imbalance and Kidney Damage in Cafeteria Diet-Induced Rat Model of Metabolic Syndrome: Effect of Bergamot Polyphenolic Fraction
Beta-Cryptoxanthin 📋 36835262β-Cryptoxanthin Maintains Mitochondrial Function by Promoting NRF2 Nuclear Translocation to Inhibit Oxidative Stress-Induced Senescence in HK-2 Cells
Bitter Melon 📋✍⛔35023522The novel anti-inflammatory activity of mcIRBP from Momordica charantia is associated with the improvement of diabetic nephropathy
Black Pepper 📋✍⛔25572733Immunopathological and antimicrobial effect of black pepper, ginger and thyme extracts on experimental model of acute hematogenous pyelonephritis in albino rats
Black Tea 📋✍⛔35059399Isothiocyanate From Moringa oleifera Seeds Inhibits the Growth and Migration of Renal Cancer Cells by Regulating the PTP1B-dependent Src/Ras/Raf/ERK Signaling Pathway
Blackberry 📋 ⛔31040041Blackberry juice anthocyanidins limit cisplatin-induced renal pathophysiology in mice
Blueberry 📋✍⛔30865689The natural drug DIAVIT is protective in a type II mouse model of diabetic nephropathy
Boron 📋✍⛔31446563Boron, a Trace Mineral, Alleviates Gentamicin-Induced Nephrotoxicity in Rats
Broccoli 📋 ⛔35035501The Effect of Broccoli Extract in Arsenic-Induced Experimental Poisoning on the Hematological, Biochemical, and Electrophoretic Parameters of the Liver and Kidney of Rats
Burdock 📋 ⛔34955856Burdock Fructooligosaccharide Attenuates High Glucose-Induced Apoptosis and Oxidative Stress Injury in Renal Tubular Epithelial Cells
Butter 📋 ⛔37900086The effect of nutritional factors on urolithiasis: A case-control study
Camellia 📋 ⛔38068746Virgin Camellia Seed Oil Improves Glycolipid Metabolism in the Kidney of High Fat-Fed Rats through AMPK-SREBP Pathway
Cannabidiol Oil 📋✍⛔37971510Prospective affirmative therapeutics of cannabidiol oil mitigates doxorubicin-induced abnormalities in kidney function, inflammation, and renal tissue changes
Captopril 📋 26398443Effects of Curcumin and Captopril on the Functions of Kidney and Nerve in Streptozotocin-Induced Diabetic Rats: Role of Angiotensin Converting Enzyme 1
Cardamom 📋✍⛔37318456Protective effect of ethanolic extract of Elettaria Cardamomum against gentamicin hepato-renal toxicity in male albino rats
Carnosol 📋 36552549Protective Effects of Carnosol on Renal Interstitial Fibrosis in a Murine Model of Unilateral Ureteral Obstruction
Cat's Claw 📋✍⛔21445508[Uncaria tomentosa and acute ischemic kidney injury in rats]
Celery 📋 ⛔34774409Nephroprotective effect of Tukhm-e-Karafs (Apium graveolens L.) against Cisplatin-induced nephrotoxicity
Chamomile 📋✍⛔34764746Chamomile flower extract ameliorates biochemical and histological kidney dysfunction associated with polycystic ovary syndrome
Chicoric Acid 📋 38525833Chicoric acid advanced PAQR3 ubiquitination to ameliorate ferroptosis in diabetes nephropathy through the relieving of the interaction between PAQR3 and P110α pathway
Chicory 📋✍⛔38031637Protective effect of chicory and/or artichoke leaves extracts on carbon tetrachloride and gamma-irradiation-induced chronic nephrotoxicity in rats
Chromium 📋✍⛔33312555An antidiabetic nutraceutical combination of red yeast rice ( Monascus purpureus), bitter gourd ( Momordica charantia), and chromium alleviates dedifferentiation of pancreatic β cells in db/db mice
Cinnamic Acid 📋 38347789Uncovering the Mechanisms of Cinnamic Acid Treating Diabetic Nephropathy Based on Network Pharmacology, Molecular Docking, and Experimental Validation
Clove 📋 ⛔15934019Antioxidant activity of DHC-1, an herbal formulation, in experimentally-induced cardiac and renal damage
Conjugated Linoleic Acid 📋✍⛔18629561Dietary Conjugated Linoleic Acid Renal Benefits and Possible Toxicity Vary With Isomer, Dose and Gender in Rat Polycystic Kidney Disease
Costus 📋✍⛔34486350Nephroprotective Effect of Costus ( Saussurea costus) Ethanolic Extract on Oxaliplatin ®-induced Nephrotoxicity in Adult Male Wistar Rats
Coumaric acid 📋 24060003p-Coumaric acid, a common dietary polyphenol, protects cadmium chloride-induced nephrotoxicity in rats
Creatine 📋✍⛔12969151Creatine Supplementation Decreases Homocysteine in an Animal Model of Uremia
D-Limonene 📋✍⛔33510839D-Limonene Alleviates Acute Kidney Injury Following Gentamicin Administration in Rats: Role of NF- κ B Pathway, Mitochondrial Apoptosis, Oxidative Stress, and PCNA
Dairy 📋 36270480High-fat dairy products may decrease the risk of chronic kidney disease incidence: A long-term prospective cohort study
Delphinidin 📋 30865689The natural drug DIAVIT is protective in a type II mouse model of diabetic nephropathy
Eclipta Alba 📋✍ 34949157The nephroprotective effects of Daucus carota and Eclipta prostrata against cisplatin-induced nephrotoxicity in rats
Escin 📋✍⛔28075477Escin induces apoptosis in human renal cancer cells through G2/M arrest and reactive oxygen species-modulated mitochondrial pathways
Eucalyptus 📋✍⛔33134128Eucalyptus Globulus protects against diclofenac sodium induced hepatorenal and testicular toxicity in male rats
Fennel 📋✍⛔36829884Nephroprotective Effect of Fennel ( Foeniculum vulgare) Seeds and Their Sprouts on CCl4-Induced Nephrotoxicity and Oxidative Stress in Rats
Fish 📋 ⛔35631289Association of Dietary Fish and n-3 Unsaturated Fatty Acid Consumption with Diabetic Nephropathy from a District Hospital in Northern Taiwan
Fish Collagen 📋✍⛔35223948Using Collagen Peptides From the Skin of Monkfish ( Lophius litulon) to Ameliorate Kidney Damage in High-Fat Diet Fed Mice by Regulating the Nrf2 Pathway and NLRP3 Signaling
Forskolin 📋✍⛔35512548Forskolin alleviates cisplatin-induced acute renal toxicity in rats
Gamma-Linolenic Acid 📋✍⛔23074118Gamma linolenic acid exerts anti-inflammatory and anti-fibrotic effects in diabetic nephropathy
Genipin 📋 33792721Effect of genipin-1-β-d-gentiobioside on diabetic nephropathy in mice by activating AMP-activated protein kinase/silencing information regulator-related enzyme 1/ nuclear factor-κB pathway
Giloy 📋✍⛔35383764Protective and Curative Effects of Ethanol extract of Tinospora Cordifolia on Gentamicin-induced Nephrotoxicity in Rats
Ginkgolic Acid 📋 32256780Ginkgolic acid inhibits the growth of renal cell carcinoma cells via inactivation of the EGFR signaling pathway
Glabridin 📋 35596156Glabridin, a bioactive component of licorice, ameliorates diabetic nephropathy by regulating ferroptosis and the VEGF/Akt/ERK pathways
Graviola 📋✍⛔38362149Annona Muricata L. extract restores renal function, oxidative stress, immunohistochemical structure, and gene expression of TNF-α, IL-β1, and CYP2E1 in the kidney of DMBA-intoxicated rats
Helichrysum 📋 ⛔25617747Preventive treatment of calcium oxalate crystal deposition with immortal flowers
Holy Basil 📋✍⛔33642811The protective effect of Ocimum sanctum leaf extract against lead acetate-induced nephrotoxicity and hepatotoxicity in mice ( Mus musculus)
Honeysuckle 📋 ⛔35355712An Optimized Two-Herb Chinese Food as Medicine Formula Reduces Cisplatin-Induced Nephrotoxicity in the Treatment of Lung Cancer in Mice
Horny Goat Weed 📋✍⛔34994765Total flavonoids in Epimedium koreanum Nakai alleviated chronic renal failure via promoting AMPK activation
Horse Chestnut 📋✍⛔27424320The efficacy of Aesculus hippocastanum seeds on diabetic nephropathy in a streptozotocin-induced diabetic rat model
Horsetail Grass 📋✍⛔33747109Phytochemistry and Pharmacology of the Genus Equisetum (Equisetaceae): A Narrative Review of the Species with Therapeutic Potential for Kidney Diseases
Hypericin 📋 38547517Hypericin alleviates Chronic Kidney Disease induced Left Ventricular Hypertrophy via regulation of FGF23-FGFR4 signaling pathway
Isoflavones 📋✍⛔35807748Isoflavone Protects the Renal Tissue of Diabetic Ovariectomized Rats via PPARγ
Isoquercitrin 📋 38666938In Silico and In Vitro Study of Isoquercitrin against Kidney Cancer and Inflammation by Triggering Potential Gene Targets
Jasmine 📋 ⛔36144196Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation
Jojoba Oil 📋✍⛔33481197Ameliorative effects of jojoba oil on fipronil-induced hepatorenal- and neuro-toxicity: the antioxidant status and apoptotic markers expression in rats
Kiwifruit 📋✍⛔28759758Kiwi fruit (Actinidia deliciosa) ameliorates gentamicin-induced nephrotoxicity in albino mice via the activation of Nrf2 and the inhibition of NF-κB (Kiwi & gentamicin-induced nephrotoxicity)
Krill Oil 📋✍⛔35916281Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy
L-Alanine 📋✍⛔33454690THE EFFECTS OF L-ORNITINE AND L-ARGININE ON THE PROCESSES OF LIPID PEROXIDATION IN THE FUNCTIONAL LAYERS OF KIDNEYS ON THE BACKGROUND OF ACUTE TOXIC HEPATITIS
L-Lysine 📋✍⛔36132073L-Lysine Ameliorates Diabetic Nephropathy in Rats with Streptozotocin-Induced Diabetes Mellitus
L-Methionine 📋✍⛔37931136L-methionine protects against nephrotoxicity induced by methotrexate through modulation of redox status and inflammation
L-Ornithine 📋✍⛔33454690THE EFFECTS OF L-ORNITINE AND L-ARGININE ON THE PROCESSES OF LIPID PEROXIDATION IN THE FUNCTIONAL LAYERS OF KIDNEYS ON THE BACKGROUND OF ACUTE TOXIC HEPATITIS
L-Tryptophan 📋✍⛔33218054Developmental Programming and Reprogramming of Hypertension and Kidney Disease: Impact of Tryptophan Metabolism
Lavender Essential Oil 📋✍⛔30453254Lavender oil (Lavandula angustifolia) attenuates renal ischemia/reperfusion injury in rats through suppression of inflammation, oxidative stress and apoptosis
Lentil 📋 ⛔36438775Antioxidative potential and ameliorative effects of green lentil ( Lens culinaris M.) sprouts against CCl4-induced oxidative stress in rats
Lettuce 📋 ⛔35392648Lettuce as an Effective Remedy in Uremic Pruritus: Review of the Literature Supplemented by an In Silico Study
Lingonberry 📋 ⛔32292787Inhibition of Inflammatory Cytokine Expression Prevents High-Fat Diet-Induced Kidney Injury: Role of Lingonberry Supplementation
Loquat 📋✍⛔37498560Polyphenol-rich extract from loquat fruit peel prevents hyperlipidemia and hepato-nephrotoxicity in mice: in vivo study and in silico prediction of possible mechanisms involving identified polyphenols and/or their circulating metabolites
Lychee 📋 ⛔33470120Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats
Madecassoside 📋 38056145Madecassoside alleviates acute kidney injury by regulating JNK-mediated oxidative stress and programmed cell death
Magnolol 📋 35385419Magnolol reduces myocardial injury induced by renal ischemia and reperfusion
Malvidin 📋 38135199Malvidin promotes PGC-1α/Nrf2 signaling to attenuate the inflammatory response and restore mitochondrial activity in septic acute kidney injury
Milk 📋 ⛔36270480High-fat dairy products may decrease the risk of chronic kidney disease incidence: A long-term prospective cohort study
Morusin 📋 32355771Morusin exerts anti-cancer activity in renal cell carcinoma by disturbing MAPK signaling pathways
Mucuna Pruriens 📋✍⛔34789221Ethanolic extract of Mucuna pruriens leaves ameliorates carbon tetrachloride and rifampicin-induced hepatotoxicity and nephrotoxicity in wistar albino rat
Mustard 📋 ⛔37959024The Nephroprotective Potential of Brassica nigra Sprout Hydroalcoholic Extract against Carbon Tetrachloride-Induced Renal Toxicity in Rats
Myrrh 📋✍⛔29990838Commiphora molmol protects against methotrexate-induced nephrotoxicity by up-regulating Nrf2/ARE/HO-1 signaling
Myrrh Essential Oil 📋 ⛔36826023Myrrh Essential Oil Mitigates Renal Ischemia/Reperfusion-Induced Injury
Myrtle 📋✍⛔33475094Myrtus communis improves cognitive impairment in renovascular hypertensive rats
Nattokinase 📋✍⛔30788657Nattokinase-heparin exhibits beneficial efficacy and safety-an optimal strategy for CKD patients on hemodialysis
Neohesperidin 📋 36608504Neohesperidin dihydrochalbazone protects against septic acute kidney injury in mice
Nimbolide 📋 35143824Co-treatment of Nimbolide augmented the anti-arthritic effects of methotrexate while protecting against organ toxicities
Nuts 📋 ⛔35609522Nut Consumption and Effects on Chronic Kidney Disease and Mortality in the United States
Oats 📋 ⛔35614982Oat β Glucan Ameliorates Renal Function and Gut Microbiota in Diabetic Rats
Okra 📋 ⛔36276416The effect of Abelmoschus esculentus L. (Okra) extract supplementation on dietary intake, appetite, anthropometric measures, and body composition in patients with diabetic nephropathy
Oleic Acid 📋 ⛔34798521Oleic acid alleviates LPS-induced acute kidney injury by restraining inflammation and oxidative stress via the Ras/MAPKs/PPAR-γ signaling pathway
Oregano Essential Oil 📋✍⛔38256015Oregano ( Origanum vulgare) Essential Oil and Its Constituents Prevent Rat Kidney Tissue Injury and Inflammation Induced by a High Dose of L-Arginine
Patchouli 📋✍⛔37177974Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway
PEA 📋✍⛔25981305Effects of Palmitoylethanolamide and Silymarin Combination Treatment in an Animal Model of Kidney Ischemia and Reperfusion
Peach 📋 ⛔33604381Using Network Pharmacology to Explore the Mechanism of Peach Kernel-Safflower in the Treatment of Diabetic Nephropathy
Peony 📋 ⛔37599498Paeony attenuates high fat diet-induced kidney injury via inflammation inhibition
Phosphatidylserine 📋✍⛔37666289Investigation of the potential ameliorative effects of DHA-enriched phosphatidylserine on bisphenol A-induced murine nephrotoxicity
Pineapple 📋✍⛔33583802Antinephrolithiatic activity of Ananas comosus extract against experimentally induced renal calculi in rats
Piperlongumine 📋 37121453Piperlonguminine attenuates renal fibrosis by inhibiting TRPC6
Prebiotics 📋✍⛔36618701Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010-2020
Proanthocyanidins 📋 36935438Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in renal ischemia-reperfusion injury model of mice
Procyanidins 📋 ⛔35861207Beneficial effects of procyanidin B2 on adriamycin-induced nephrotic syndrome mice: the multi-action mechanism for ameliorating glomerular permselectivity injury
Protein 📋✍⛔37211392Total protein intake and subsequent risk of chronic kidney disease: the Circulatory Risk in Communities Study
Psyllium 📋✍⛔37017261Psyllium seed husk regulates the gut microbiota and improves mucosal barrier injury in the colon to attenuate renal injury in 5/6 nephrectomy rats
Pu-erh Tea 📋✍⛔22482420Inhibition of advanced glycation end product formation by Pu-erh tea ameliorates progression of experimental diabetic nephropathy
Rosehip 📋✍⛔34135957Protective Effects of Hydroalcoholic Extract of Rosa canina Fruit on Vancomycin-Induced Nephrotoxicity in Rats
Safflower 📋✍⛔33604381Using Network Pharmacology to Explore the Mechanism of Peach Kernel-Safflower in the Treatment of Diabetic Nephropathy
Safranal 📋 26468467Histopathological and Behavioral Evaluations of the Effects of Crocin, Safranal and Insulin on Diabetic Peripheral Neuropathy in Rats
Sage Essential Oil 📋 ⛔30056541Carbon tetrachloride induced hepato/renal toxicity in experimental mice: antioxidant potential of Egyptian Salvia officinalis L essential oil
Seafood 📋 36653033Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts
Seaweeds 📋 ⛔35525730Sulfated Undaria pinnatifida polysaccharide inhibits the formation of kidney stones by inhibiting HK-2 cell damage and reducing the adhesion of nano‑calcium oxalate crystals
Senolytics 📋 36384564The diseased kidney: aging and senescent immunology
Sesame 📋✍⛔32432778Sesame lignans suppress age-related disorders of the kidney in mice
Sesamolin 📋 36630317Sesamolin Attenuates Kidney Injury, Intestinal Barrier Dysfunction, and Gut Microbiota Imbalance in High-Fat and High-Fructose Diet-Fed Mice
Shiitake Mushrooms 📋✍⛔38417905The Tumor Growth Inhibitory Effect of a Standardized Extract of Cultured Lentinula edodes Mycelia Using Patient Derived Xenograft Model
Sirtuin Activators 📋 35774140Sirtuin Family and Diabetic Kidney Disease
Stevia 📋✍⛔31569913Effects of exercise and stevia on renal ischemia/reperfusion injury in rats
Stigmasterol 📋 27784187Renoprotective effect of Bacopa monnieri via inhibition of advanced glycation end products and oxidative stress in STZ-nicotinamide-induced diabetic nephropathy
Sulfur 📋✍⛔37367846Sulfur-Containing Amino Acids, Hydrogen Sulfide, and Sulfur Compounds on Kidney Health and Disease
Sweet Potato 📋 ⛔34981522In vitro and in vivo ameliorative effects of polyphenols from purple potato leaves on renal injury and associated inflammation induced by hyperuricemia
Tamarind 📋 ⛔36003506The Combination of Tamarindus indica and Coenzyme Q10 can be a Potential Therapy Preference to Attenuate Cadmium-Induced Hepatorenal Injury
Theobromine 📋✍⛔37446053Efficacy of Theobromine and Its Metabolites in Reducing the Risk of Uric Acid Lithiasis
Tomato 📋 ⛔37692132Effects of lemon-tomato juice consumption on crystal formation in the urine of patients with calcium oxalate stones: A randomized crossover clinical trial
Trans-Resveratrol 📋 29229234Trans-resveratrol mitigates type 1 diabetes-induced oxidative DNA damage and accumulation of advanced glycation end products in glomeruli and tubules of rat kidneys
Turmeric 📋✍⛔35714209Efficacy and Safety of Turmeric Dietary Supplementation on Proteinuria in CKD: A Systematic Review and Meta-analysis of RCT
Vegetables 📋 17164369Intakes of fruits, vegetables, vitamins A, C, and E, and carotenoids and risk of renal cell cancer
Vitamin B1 📋✍⛔30704890Vitamin B complex supplementation as a homocysteine-lowering therapy for early stage diabetic nephropathy in pediatric patients with type 1 diabetes: A randomized controlled trial
Vitamin B2 📋✍⛔37237348The association of dietary intake of riboflavin and thiamine with kidney stone: a cross-sectional survey of NHANES 2007-2018
Vitamin B8 📋✍⛔36611810Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis
Vitamin K2 mk-4 📋✍ 14712427Protective Effect of Vitamins K2 and D3 on Prednisolone-Induced Loss of Bone Mineral Density in the Lumbar Spine
Vitamin K2 mk-7 📋✍ 35139790Vitamin K supplementation in chronic kidney disease patients: where is the evidence?
Watermelon 📋 ⛔34841269Watermelon rind ethanol extract exhibits hepato-renal protection against lead induced-impaired antioxidant defenses in male Wistar rats
Whey Protein 📋✍⛔36950976Whey Protein Concentrate Ameliorates the Methotrexate-Induced Liver and Kidney Damage
White Tea 📋 ⛔33577915Ameliorative effect of white tea from 50-year-old tree of Camellia sinensis L. (Theaceae) on kidney damage in diabetic mice via SIRT1/AMPK pathway
Wormwood Essential Oil 📋 ⛔33716767Antioxidant and Protective Effects of Artemisia campestris Essential Oil Against Chlorpyrifos-Induced Kidney and Liver Injuries in Rats
Yerba Mate 📋✍⛔37219520Beneficial effects of mate-herb, Ilex paraguariensis St. Hil. against potassium dichromate-induced oxidative stress and nephrotoxicity
Yogurt 📋 ⛔36618701Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010-2020
Zeaxanthin 📋✍⛔28058588The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats